1. What are breast calcifications? Show
1. What are breast calcifications?Breast calcifications are small dots of calcium salts that can occur anywhere in the breast tissue. They are very small so you won’t be able to feel them, and they don’t cause any pain. Breast calcifications are very common. They are usually due to benign (not cancer) changes that occur as part of aging. Sometimes they form because of other benign changes in the breast, such as a fibroadenoma or breast cyst. They can also form if you’ve had an infection in your breast, if you’ve injured your breast, or if you’ve had surgery or a breast implant. Breast calcifications can develop in the blood vessels of the breast. These may be age-related or caused by other medical conditions but don’t usually require further assessment. Breast calcifications are more common in women, but can also be found in men. Occasionally, breast calcifications can be an early sign of cancer. Because of this, you may need further tests to check what sort of calcifications you have. 2. How are breast calcifications found?Breast calcifications are usually found by chance during a routine screening mammogram or during an investigation at a breast clinic for another breast problem. The calcifications show up on a mammogram as small white dots. When you have a mammogram, the image is looked at by one or more radiologists or specialist practitioners (doctors and other trained staff who specialise in the use of imaging to diagnose and treat disease). When calcifications are found, they will look carefully at:
They will categorise the calcifications as looking benign, indeterminate (uncertain) or suspicious of being cancer. Types of breast calcificationsMicrocalcifications are small. They often occur because of benign (not cancer) changes, but occasionally microcalcifications can be an early sign of cancer. Macrocalcifications are larger. They usually occur because of benign (not cancer) changes and do not need to be investigated. 3. How are breast calcifications treated?If the calcifications look benign, nothing more needs to be done. They don’t need to be removed and won’t cause you any harm. If the calcifications look indeterminate (uncertain) or suspicious you will need further tests, as in many cases a mammogram won’t give enough information. This doesn’t mean something is wrong, but further tests will help to make an accurate diagnosis. These tests are usually done in the breast clinic or x-ray department as an outpatient. You won’t have to stay overnight in hospital. Further tests could include the following: MammogramYou may need to have another mammogram that gives a close-up (magnified) picture of the affected area. Ultrasound scanAn ultrasound scan uses sound waves to produce an image of the breast tissue. It’s painless, and generally done in a few minutes but can take longer. Core biopsyA core biopsy uses a hollow needle to take a sample of breast tissue, and is done using a mammogram or ultrasound for guidance. The sample will be sent to a laboratory to be looked at under a microscope. Several tissue samples may be taken at the same time. This procedure will be done using a local anaesthetic. Because calcifications are so small, a mammogram is often used to locate them accurately. A biopsy can then be taken from the affected area (known as a stereotactic core biopsy). Vaccuum assisted biopsyThis procedure takes a little longer than a core biopsy and is done using a mammogram or ultrasound for guidance. After an injection of local anaesthetic, a small cut is made in the skin. A hollow probe connected to a vacuum device is placed through this cut. Breast tissue is then sucked through the probe by the vacuum into a collecting chamber. This means that several samples of breast tissue can be collected without removing the probe. The samples are sent to a laboratory to be examined under a microscope. Vacuum assisted excision biopsyOccasionally, you may have a vacuum assisted excision biopsy to remove an area of calcification. This is a similar procedure to a vacuum assisted biopsy, but more tissue may be removed. This may mean that an operation under a general anaesthetic can be avoided. Find more information about these tests » Inserting a metal markerSometimes a small metal clip (or marker) may be placed in the breast where the biopsy has been taken. This is so the area can easily be found again if a further biopsy or surgery is necessary. If another procedure isn’t needed, the clip can be safely left in the breast. The marker clip is usually made of titanium (the same metal used for joint replacement surgery). It will not set off alarms at airports. Most clips are now suitable for having an MRI, but if the marker clip is left in and you need to have an MRI scan in the future, let your doctor or radiographer know. LocalisationYou may be recommended an operation to remove the area of calcification if it’s not possible to get a biopsy of the area, or if the biopsy did not confirm a diagnosis. You may also need an operation if the biopsy results show an unusual change (called atypia), or the biopsy results show a sign of early cancer. Because the calcification cannot usually be felt, the exact position has to be ‘marked’ for the surgeon, so that they can remove the right area. In this case a technique called wire localisation is used. In the x-ray department, a mammogram or ultrasound scan will be used as a guide to insert a fine wire into the breast under local anaesthetic. The wire is then carefully secured under a small dressing and left in place until the operation to remove the area of calcification. The operation is usually done under a general anaesthetic on the same day, and the wire will be removed during the operation. Some hospitals are using a new localisation procedure. Instead of a fine wire a tiny, very low dose radioactive seed (about the size of a grain of rice) or a small radiation-free magnetic marker (known as a Magseed) is inserted into the breast tissue. This can be done up to two weeks before your operation. During surgery, a special probe is used to locate the seed and guide the surgeon to the tissue that needs to be removed. The seed will be removed during the operation. Sometimes the operation is done on a different day and in this case you’ll go home after the wire or seed has been inserted, and come back to the hospital the day of your operation. If the wire or seed feels uncomfortable while it is in place you can have mild pain relief, such as paracetamol. After your operation, you may feel soreness and discomfort but this can be managed with pain relief. There will be a scar, but this should fade in time. 4. Follow-upIt’s likely that your tests will show the calcifications are due to benign changes, and in this case you won’t need any more treatment. If the calcifications are part of another benign breast condition or an unusual change (called atypia), you will be told if anything else needs to be done. You may also find it helpful to read our information about benign breast conditions. If you’re told that the calcifications are an early sign of breast cancer, your treatment team will talk to you about what this means and discuss your future treatment. 5. Do breast calcifications increase my risk of breast cancer?Most breast calcifications are due to benign (not cancer) changes, which does not increase your risk of breast cancer. However, if the breast calcifications are due to atypical change, this may slightly increase your risk of breast cancer. Your treatment team will be able to discuss this further with you. It’s important to continue to be breast aware, and to go back to your GP if you notice any changes in your breasts, however soon this is after you were told you had calcifications. Find out more about being breast aware » 6. Further supportHaving breast calcifications may make you feel anxious and in need of further support. If you have any questions about breast calcifications or would just like to talk it through with an expert, you can call our free Helpline on 0808 800 6000. Breast calcifications are small deposits of calcium in the breast tissue. They often show up in mammograms and are most common in women over 50. Breast calcifications are typically noncancerous, or benign. However, some forms can occasionally indicate breast cancer. This article looks at the causes of breast calcifications, and we discuss what may happen if they show up on a screening test. Share on PinterestJupiterimages/Getty Images Calcifications are small calcium deposits that develop in the breasts. They do not cause symptoms, and a doctor cannot diagnose them from a routine breast check. Instead, they typically appear as white dots on a mammogram, which is an X-ray of the breasts. Other breast scans, such as ultrasounds or MRI scans, do not show calcifications. Calcifications are more likely to develop after menopause. Most breast calcifications are benign. However, clusters of calcium deposits can suggest early breast cancer. Some research indicates 12.7–41.2% of women in screening programs with breast calcifications are brought back for additional clinical assessment as the only warning sign of cancer. While calcifications do not develop into cancer, they can suggest an underlying process that is connected to breast cancer. Two types of breast calcifications can appear on mammograms — macrocalcifications and microcalcifications. Some women have a mix of both. MacrocalcificationsMacrocalcifications appear as large white dots that occur randomly throughout the breast tissue. They are greater than 0.5 millimeters (mm) in diameter. Macrocalcifications are very common, and doctors usually consider them to be benign. As a result, people with macrocalcifications in the breast usually require no follow-up testing. MicrocalcificationsMicrocalcifications appear as tiny white specks or grains. Many cases of microcalcifications are benign. However, if they have certain characteristics, they may indicate an underlying cancerous process. Doctors usually regard microcalcifications as suspicious and in need of further investigation if they have the following characteristics:
Although this number is not definitive, a cluster generally consists of at least 3-5 calcifications. Loose clusters are more likely to be benign than compact clusters. Calcifications outside the main breast tissueOccasionally, a mammogram may show calcifications outside of the main breast tissue. These may appear to be on the skin or inside the blood vessels. Those on the skin may be due to deodorant, lotions, or powder residue that causes white dots to appear on the X-ray results. For this reason, people should avoid applying any skin products before the screening. Once the radiologist confirms the location as being outside of the breast tissue itself, then these types of calcifications require no further testing. Calcifications can occur in the breast tissue as a result of: Any of the above factors can cause breast calcifications to develop. DCIS is the most common type of cancer diagnosed in people with breast calcifications. A 2019 study also suggested a link between lifetime breastfeeding duration and the presence of microcalcification clusters. The report assessed the association of microcalcification clusters with multiple breast cancer risk factors. Other factors that increase risk include:
Eating calcium-rich foods does not cause breast calcifications. If calcifications appear on a mammogram, the radiologist will decide if further investigation is necessary. Generally, they do not consider macrocalcifications suspicious. Standard sizes and shapes of calcifications are also less likely to require a follow-up. However, if large calcifications occur in clusters or alongside microcalcifications, the radiologist may advise further testing. If they consider the calcifications to be suspicious, they may:
A doctor may:
People who have a history of breast cancer or are at a high risk of cancer development should see their doctor if calcifications appear on a mammogram. A doctor will consider these risk factors when deciding on further testing. A breast biopsy involves removing a small piece of breast tissue to examine it closely. There are two types of biopsies to test breast calcifications. Stereotactic core needle biopsy is when a doctor inserts a needle into the breast, using computer imaging, to remove a piece of calcification tissue under local anesthetic. A surgical biopsy is when a surgeon removes the abnormal tissue sample under local or general anesthetic and sends it to a lab for examination. Doctors typically only perform a surgical biopsy if a core needle biopsy is unsuccessful or if the results are inconclusive. Before undergoing a surgical biopsy, individuals should discuss scarring, anesthesia, or recovery concerns with their surgeon. Benign calcifications do not require any treatment. However, if the calcifications are associated with another medical condition, such as mammary duct ectasia, a doctor will provide the person with more information on the condition and available treatments. If the calcifications indicate breast cancer, the person will require treatment to stop the spread of cancer and kill the cancerous cells. The type of treatment a person will need depends on the type of breast cancer, its size and stage, and other factors. Potential treatments for breast cancer include:
Breast calcifications can indicate early breast cancer, which highlights the importance of having regular screening mammograms. However, most calcifications are benign and do not need follow-up investigations or treatment. If a radiologist considers the calcifications suspicious, they will perform another mammogram and may recommend a biopsy. Read the article in Spanish. |