A nurse is caring for a client who has a new prescription for pramipexole to treat parkinsons

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Levodopa Drug Combinations for the Treatment of Parkinson’s Disease

MedicationAvailable DosesInitial Dosing
Carbidopa/levodopa (Sinemet)10/100 mg 25/100 mg

50/250 mg

25/100 mg two to three times per day
Carbidopa/levodopa controlled-release (Sinemet CR)50/250 mg50/250 mg twice daily
Carbidopa/levodopa/entacapone (Stalevo)12.5/50/250 mg 25/100/250 mg 37.5/150/250 mg

50/200/200 mg

12.5/50/250 mg
Carbidopa/levodopa orally disintegrating tablet (Parcopa)10/100 mg 25/100 mg

25/250 mg

25/100 mg two or three times per day